tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride (1023301-84-9)

(2 kasitoma wongororo)

Ichi chigadzirwa (s) chinogara pane kambani ye APICMO.

Kukwanisa kubudisa, kugadzira uye kugadzira zvakawanda zvett-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride (1023301-84-9) nehutano hwehutsika pasi peCGMP
mitemo.

SKU: 1023301-84-9 Category:

tsananguro

ganda-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride (1023301-84-9) video

Tert-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride, iyo inogamuchirwa mishonga inogamuchirwa, ester, solvate iyo, inobatsira pakurapa zvirwere umo kunorambidzwa kweprotheni kana lipid kinase (semuenzaniso PIM mhuri kinase, yakadai PIM-1, PIM-2 uye / kana PIM-3) inoda uye / kana inoda, kunyanya mukurapa kenza kana chirwere chinopfuurira.

Mazita emakemikari ayo mazita e-t-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride, tert-butyl-2,7-diazaspiro [3,5] isina-7-carboxylate hydrochloride, tert-butyl 2,7-diazaspiro [3.5] isina-7- carboxylate hydrochloride, tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate, 2,7-diaza-spiro [3.5] isina-7-carboxylic acid tert-butyl ester hydrochloride.

Ichi chigadzirwa (s) chinogara pane kambani ye APICMO. Kana uri kutarisa peji ino somunhu asina kubhadhara, mutengo (s) unoratidzirwa ndiNhamba yeZveruzhinji. Kuti uone kutengesa kwako, pinda mukati uchishandisa nhamba yako yekodha, kana kuti iwe unyoresa waunoshandisa kuburikidza neimwe yemakambani eChipatimendi Chebasa. Kuti uise mutemo, taura ne APICMO Customer Service.

ganda-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride (1023301-84-9) Tsanangudzo

CAS 1023301-84-9
CAS Min% 97.0
CAS Max% 98.0
MDL Nhamba MFCD13185086
InChI Key HVLQURGQQISYSQ-UHFFFAOYSA-N
Kemikari Zita kana Nyaya Tsi-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride
Infrared Spectrum N / A
Physical Form I-ye-white hoig inopisa
Packaging Bhodhoro regirazi
Molecular Formula C12H23ClN2O2
Molecular Weight (g / mol) 261.76828
SMILES Cl.O = C (OC (C) (C) C) N2 (CCC1 (CNC1) (CC2))
ruvara tsvukuruka
Melting Point 50.1 - 158 ° C
Assay ≧ 98%

ganda-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride (1023301-84-9) Kuchengetedza uye Kugadzirisa

dutu-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride Dambudziko rekushandisa:APICMO hazard icons

w Ndingaita kuti ganda rinogadzirisa

w Unokonzera kusuruvara kweziso

1023301-84-9 Precautionary statement:

w Dzivisa kufema kufema / fume / gasi / mhepo / mhepo / spray.

w Pfeka gasikudzivirira nekudzivirira kweziso / chiso.

w KANA MUMWE EYES: Isai nokungwarira nemvura kwemaminitsi akawanda. Bvisa manotsi lenzi, kana zviripo uye zviri nyore kuita. Rambai muchigadzira.

w KANA UCHISHA: Bvisa mweya wakachena uye urambe uchizorora uri mukana wakasununguka kufema.

w Chengetedza yakavharwa.

w Zvinyorwa zviri mukati maro / mudziyo maererano nemunharaunda / mahara / nyika /

international rules.

YAMBIRO: Mashoko aya anowanikwa pane iyi webhupu yakagadziridzwa maererano nemitemo yeEuropean Union (EU) uye yakarurama kune zvakanakisisa zvezivo yedu, ruzivo uye rutendo pazuva rawakabudiswa. Mashoko anopiwa anogadzirirwa chete semutungamiri wekusachengetedza nekuchengetedza zvakachengeteka. Izvo hazvifaniri kuonekwa sechirango kana kuti maitiro ehutano.

Articles

SUBSTITUTED PIPERIDINE COMPOUNDS

Piperidine inogadzira sariti inogamuchirwa nesarvates iyo mumishonga, inonyanya kukosha mukurapa kenza.

WO2016 / 40515, 2016

Tsi-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride (1023301-84-9) Zvebasa Service:

Bato revasayendisiti vane ruzivo munharaunda dzose dzekutsvakurudza kusanganisira Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical nezvimwe zvizhinji.

Tet-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride (1023301-84-9) Kurayira Kuwanda & Kutengo:

Iwe unoda huwandu hwakawandisa nokuda kwekutsvaga kwako, kushandiswa kana kutsvakurudza zvese?


=

2 anodzokorora nokuti tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride (1023301-84-9)

  1. APICMO -

    Uri kutsvaga nzvimbo yekutenga yakawanda yeTt-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride (1023301-84-9)? Iwe haufaniri kushushikana nokuti tine unyanzvi uye ruzivo rwakakura pakugadzira uye kubudisa zvizhinji zvechigadzirwa. Zvigadzirwa zvedu zvose zvinobudiswa pasi pezvinotarisirwa zvekutengesa mitemo yeCGMP.

    Tert-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride tsanangudzo

    Tert-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride ine mishonga inogamuchirwa ester, solvate, munyu inobatsira mukurapa zvirwere zvinoda kubviswa kwe lipid kinase kana kuti protein (zvichienderana ne kinase yemhuri yePIM yakafanana PIM-3, PIM-2or PIM-1) kuwedzera kunyanya mukurapa zvirwere zvinopararira kana kenza.

    Ichi chigadzirwa chiri muchikwata chemavara emhepo.

    Chimiro chimiro che Tert-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride

    tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride (1023301-84-9)

    Chigadzirwa chacho chinoshandisa nzira imwe chete:

    Synthesis Route yeTert-Butyl 2,7-diazaspiro [3.5] isina-7-carboxylate hydrochloride

    tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride (1023301-84-9)

    929302-00-1
    Tet-butyl 4-c ...

    6-Chloro-5-azaindole

    tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride (1023301-84-9)1023301-84-9
    tete-butyl 2,7-d ..

    Tet-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride (1023301-84-9) ine chimwe chigadzirwa chekutanga:

    929302-00-1

    tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride (1023301-84-9)

    Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate; hydrochloride Zvichemo zvemiti:

    Product Name Tsi-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride
    IUPAC Zita tete-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate; hydrochloride
    Assay ≧ 98%
    Melting Point 50.1 - 158 ° C
    Inofadza Cl.O = C (OC (C) (C) C) N2 (CCC1 (CNC1) (CC2))
    Molecular Formula C12H22N2O2
    Inchi InChI=1S/C12H22N2O2/c1-11(2,3)16-10(15)14-6-4-12(5-7-14)8-13-9-12/h13H,4-9H2,1-3H3
    Inchi Key HVLQURGQQISYSQ-UHFFFAOYSA-N
    Casis Max 98.0%
    Cas Min 97.0%
    CAS Number 1023301-84-9
    Synonyms X8607
    TR-033844
    ganda-Butyl2,7-diazaspiro [3.5] nonane-7carboxylatehydrochloride
    Tet-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate-hydrogen chloride (1 / 1)
    Tet-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate, HCl
    1. Tsi-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride
    2. TERT-BUTYL 2,7-DIAZASPIRO [3.5] NONANE-7-CARBOXYLATE HCL
    dota-butyl 2,7-Diazaspiro (3,5) nonane-7-carboxylate HCl
    ST1070438
    3. SCHEMBL994266
    S-7188
    RP29353
    OR317165
    4. MolPort-019-918-671
    KS-0000031N
    KB-67768
    J-524427
    I14-7445
    5. HVLQURGQQISYSQ-UHFFFAOYSA-N
    GS-4200
    FT-0657364
    6. DTXSID10670470
    7. CTK4A0927
    CS-D0628
    CB-3761
    BR-24004
    AX8159775
    ANW-50261
    AKOS015844702
    AK-24004
    AB0034450
    A800561
    7-N-Boc-2,7-diazaspiro [3.5] nonane hydrochloride
    7-Boc-2,7-diaza-spiro3.5nonane
    8. 7-Boc-2,7-diaza-spiro [3.5] nonane hydrochloride
    7-Boc-2,7-diazaspiro [3.5] nonane HCl
    7- (tert-butoxycarbonyl) -7-aza-2-azoniaspiro [3.5] isina chloride
    4CH-008457
    2,7-Diazaspiro [3.5] nonane-7-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride
    2,7-Diazaspiro [3.5] nonane-7-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride (1: 1)
    9. 2,7-diazaspiro [3.5] nonane-7-carboxylic acid tert-butyl ester hydrochloride
    2,7-diaza-spiro [3.5] nonane-7-carboxylic acid tert-butyl ester hydrochloride
    1023301-84-9

    Nyama nemakemikari zvinowanikwa Tsi-Butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride

    Kushamwaridzana

    Hydrogen bond Mupi wezvipo -2 mauniti
    Acceptor count -3 units
    Rotatable bond 2 zvidzidzo
    Covalent 2 zvidzidzo

    Kuonekwa

    Tert-Butyl 2,7-diazaspiro [3.5] isina-7-carboxylate hydrochlorideappears sepoda yakachena.

    Tert-Butyl 2,7-diazaspiro [3.5] isina-7-carboxylate hydrochloride yakaumbwa nezvinhu.

    Zita Reimba ukoshi
    CACTVS Substructure Key Fingerprint AAADceBzMAAAAAAAAAAAAAAAAABYAAAA
    AAAAAAAAAAAAAAAAAAAAHgAQAAAADkTB
    gAQCCAPABAAIAAAAGAAAAAAAAAAAAIAIA
    AAAAAIAAAAAAABgCAAAAQAAALAAAAA
    AAAAAAAAAAAAAAAAAAAAAAAA ==
    Complexity 269
    Nhamba yeHeavy Atom 17
    Nhamba yeIsotopeatom 0
    Misa chaiye 226.168 g / mol.
    Mutemo Wakafanana 0
    Is The Compound Canonicalized Ehe
    Molecular Weight 262.145 g / mol.
    Monoisotopicmass 262.145 g / mol.
    Stereocenter Count of The Defined Bond 0
    Nhamba Dzakadzika dzeHasina Kuzivikanwa Atom 0
    Nhamba Dzakadzika dzeHasina Kuzivikanwa Atom 0
    Nhamba Dzakasvibiswa dzeZvisingazivikanwi Bond 0
    Nharaunda yeTopological Polar 41.6 A ^ 2

    Uses of tete-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate; hydrochloride

    Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride inobatsira mukurapa zvirwere zvinopararira kana kenza

    Kudzivirira kubata Tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride (1023301-84-9)

    APICMO hazard icons

    Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylatehydrochloride inogona kukuvadza zvinokuvadza kuhutano hwako kana zvisina kukodzera kutariswa. Saka iwe unofanirwa kuichengeta nekuchenjerera uye kutevera mirairo yose yekuchengetedza iripo.

    Njodzi dzinosanganisira tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylatehydrochloride:

    • Iyo kemikari inokonzera kuganda uye inogona kukonzera kushungurudza kunogumbura.
    • Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride iziso rinotyisa.
    • Chigadzirwa chacho hachifaniri kumira nokuti chinogona kutyisa.
    • Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride inokonzera kutsamwa kwepumusoro

    Precautionary measures

    Kuti uone kuti hauise pachena hutano hwako kune zvinetso zvinosanganiswa nechigadzirwa ichi, nguva dzose tevera zvinotevera kuchengetedzwa kwehutano hwekudzivirira iwe pachako kana uchibata chigadzirwa.

    Zvishandiso zveganda:

    Nguva dzose pfekai ganda rako nemavatya ekudzivirira.

    Chengetedza ruoko rwako kuburikidza nekushandiswa kwegorofu dzakarongedzwa zvakanaka.

    Zvishandiso zvekuchengetedzwa kweziso neziso

    Kupfeka zviyero zvekuchengetedza zvakakwana:

    Iva nechokwadi chokuti une chiso chinodzivirira kuvhara chiso chako.

    Zvombo zvokudzivirira kuputira:

    Pasi pemamiriro ezvinhu, chirwere chekuporesa chingasave chakakosha. Zvisinei, rega kuvhara gesi, guruva, mafungu, mhute, spray kana mapapiro kubva mumuumbi.

    1. Engineering measure

    Chigadzirwa chacho chinofanira kushandiswa panze kana kuti mune bhatikiti rakanyatsoputika.

    2. Matambudziko ekutanga

    Kana zviitiko zvekukurumidzira zvichiitika panguva yekubata Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylatehydrochloride, inotungamirira matanho ekutanga anobatsira asati aenda kuchipatara.

    Inhalation

    Kana mumwe munhu akabatanidza chigadzirwa chacho, chengetedze kune imwe nzvimbo nekunyorera mhepo itsva. Rega akakanganwa agare panzvimbo iyo vanogona kudzimara uye kufema zvakanaka.

    Kuisa

    Kana ikamedzwa, geza muromo nemvura yakawanda inotonhorera. Tsvaka mazano kubva kumishonga kana zviratidzo zvinoramba zvichiitika.

    Kubatana kweganda

    Bvisa zvinyorwa kubva paganda. Shenesa nzvimbo yakagadziriswa nemvura yakawanda ine mvura uye sophorera zvishoma pamusoro pemaminitsi e15. Tsvaka mazano kubva kumishonga kana kupisa kuchiwedzera.

    Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride handling measures.

    Kana iri kushandiswa

    Paunenge uchishanda ne-tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylatehydrochloride nguva dzose inofunga nezvekuchengetedza kunotevera:

    • Chengetedza muviri wako wose kusanganisira ganda, chiso, maoko, tsoka, uye maziso nemapfeko ekudzivirira uye usadzivisa kupinda mune chigadzirwa:
    • Usashandisa chigadzirwa kusvikira waverenga uye unonzwisisa mirairo.
    • Dzivisa kuumbwa kweguruva kana mafesi paunenge uchibata chigadzirwa ichi.
    • Iva nechokwadi chokuti imba yauri kushanda nayo yakanyatsonaka.
    • Shanda mune rimwe remakemikari fume chamber.
    • Usashanda pamwe nechigadzirwa ichi panguva yekuzvitakura.
    • Usadya, kunwa kana kusvuta kana uchibata chigadzirwa.
    • Usasunungura chigadzirwa mumhepo.

    Mushure mekushandisa

    Mushure mekushandisa chigadzirwa kuitisa chigadzirwa chako, tsvakurudzo kana kubudirira, funga nezvezviyero zviri pasi apa:

    • Bvisa mbatya dzakasvibiswa uye uzviputire usati watorazve.
    • Bvisa magirafu nekuchenjerera usingabatanidzi rutivi rwakasvibiswa.
    • Ventilate uye uchenese bhenji rinoshanda.
    • Shamba maoko ako uye chiso chako zvakakwana nemvura yakawanda inotonhora.
    • Dzinga mavhavha, madhawi uye zvidha zvisina chinhu maererano nedzimwe tsvina yekudzinga yemitemo kana yemitemo.
    • Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride storage.
    • Chengetedza chigadzirwa mumudziyo wakanaka.
    • Usaisa pachena chigadzirwa chezuva chairo kana kupisa.
    • Chengetedza chigadzirwa munzvimbo yakanaka.
    • Ramba uri pasi pematambo akadzika, zvichida pakati pe2 ne 8 ° C

    1. Kuramba uye reactivity

    Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride haikwirirani nemasimba anogadzirisa macidhi.

    Chibereko chacho chakasimba mumamiriro ezvinhu chaiwo.

    2. Zvichiitika kuparadzaniswa

    Kana icho chigadzirwa, zvigadzirwa zvechipiri kana kusanganiswa kwechigadzirwa nemimwe michina inodonha zvisina njodzi, tora kuparadzira zvakanyatsodzivisa kuumba guruva. Svetera uye ufukidze kuparadzanisa, kutakura dota mumatokisi emarara uye uronga kuti urege. Bvisa zvakasimba kushandiswa kwezvokudya.

    3. Kupisa moto kunodzora

    Kana tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylatehydrochloride kana michina yayo yechipiri inokonzera moto, kudzima moto uchishandisa mvura, carbon dioxide kana pfu yakaoma. Paunenge uchirwisa moto, shfeka zvipfeko zvekudzivirira uye zvinhu zvako-izvo zvine mweya yekufema. Usashandisa jet yakazara uchishandisa mvura kurwisa moto. Iwe unofanirwa kumira kurwisana nemoto kana ukasvika kumagetsi. Izvi zvinotevera fodya inokuvadza inogadzirwa ne-tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylatehydrochloride painoswa:

    • Carbon dioxide
    • Carbon monoxide
    • Nitrogen oxides
    • Hydrogen chloride
    • Phosgene

    4.Waste akadzora masimba

    Bvisa zvinhu zvose zvakasvibiswa zvinokonzerwa nekushandiswa kweTert-butyl 2,7-diazaspiro [3.5] isina-7-carboxylatehydrochloride maererano nemitemo yehurumende neyemunharaunda inorambidza kuparadzwa kwemarara.

    Package madhawi uye uzvibatise kune kambani yakagadziriswa yakashambadza tsvina.

    Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride Information Information

    Chigadzirwa chacho hachina kutaridzirwa sechinotakura kutakura nenzira ipi zvayo,, mvura, air air transport.

    Information regulatory

    Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate; hydrochloride chinhu chakakonzerwa nechinangwa chekutsvakurudza nekusimudzira. Saka hazvina kukodzera kushandiswa kwevanhu kana kwemhuka. Isu hatina kunyatsotsungiridza dambudziko, physiochemical uye zvipenyu zvechigadzirwa. Sezvo zvakadaro, kutarisira nekuremekedzwa kukuru kunofanira kuitwa apo ichiita tsvakurudzo, kubudirira kana chigadzirwa chekutanga kushandisa chigadzirwa ichi. Vashandi vakakodzera vane ruzivo mumakemikari maitiro vanofanirwa kungozviita. Inofanirawo kutarisirwa pasi pemamiriro akakodzera. Vanhu vane mutoro vachashandisa izvi kuchengetedzwa kwedzidziso pamwe chete nemashoko kubva kune mamwe mabhuku anotendeseka.

    Technical service

    Pa APICMO, tine boka reongororo rakadzidza iro rinozvipira mukutsvakurudza uye kubudirira mune zvehupenyu sayenzi, kemikari yesayenzi, kuongorora sayenzi, chromatography pakati pevamwe.

    Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate; hydrochloride (1023301-84-9) mutengo uye kuronga kwevakawanda.

    Unoda tet-butyl yakawanda 2,7-diazaspiro [3.5] nonane-7-carboxylate; hydrochloride nokuda kwekugadzirwa kwezvinhu zvako, tsvakurudzo, uye kubudirira? Iwe unogona kutaurirana nebazi redu rekutarisira vatengi uye kuita mirairo yako.

    Bibliographie

    1. National Center for Biotechnology Information, US National Library yemishonga, Pubchem, Tert-butyl 2,7-diazaspiro [3.5] nonane-7-carboxylate; hydrochloride, Zvikamu 1-9.
    2. WO2007 / 30061 A1,; Peji / Peji runyararo 92; 93; WO 2007 / 030061 A1
    3. David Robertson, Jacob J. Plattner, William K. Hagmann, Winnie W. Wong, George L. Mudzidzisi, Elsevier Sayenzi, 25 Aug 1998, Reports Gore negore muMedicine Chemistry, Bhuku 33, peji

  2. Apicmo -

    The best tert-Butyl2,7-diazaspiro [3.5] nonane-7-carboxylate hydrochloride uye basa randakave narina, Nice experience

Add kudzokorora

Your kero e haangazozikamwi ichibudiswa.