Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

Rated 5.00 Kunze kwe5 yakavakirwa 1 kasitoma Rating
(2 kasitoma wongororo)

Ichi chigadzirwa (s) chinogara pane kambani ye APICMO.

Kukwanisa kubereka, kugadzira uye kugadzira zvakawanda zvett-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) nehutano hwehutsika pasi peCGMP
mitemo.

Category:

tsananguro

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) video

Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate is spiro compound. Spiro compound ine protein kinase inhibitors, kusanganisira se c - Ita basa re tyrosine kinase inhibitor nezvimwe zvakadaro, uye rinogona kushandiswa kurapwa kweizizi dzezvirwere zvinokonzerwa nebasa risina kujairika, rakadai sekenza, kana kuti kugadzirira mishonga yekurapa zvirwere.

Its Chemical Chemotherapy is 1-oxa-6-aza-spiro- [2.5] octane-6-caboxylic acid tert-butyl ester, tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, 6-aza -6-tert-butyloxycarbonyl-1-oxaspiro <2.5> octane, 1-oxa-6-aza-spiro [2,5] octane-6-carboxylic acid tert-butyl ester, 1-oxa-6-aza-spiro [2.5] octane-6-carboxylic acid tert-butyl ester, 1,1-dimethylethyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, 1,1-dimethylethyl 1-oxa-6-azaspiro [2.5] octane -6-carboxylate.

Inoshandiswa semishonga inoshandiswa pamishonga. Inoshandiswawo sepakati pakati mune zvakagadzirwa nema organic.

Ichi chigadzirwa (s) chinogara pane kambani ye APICMO. Kana uri kutarisa peji ino somunhu asina kubhadhara, mutengo (s) unoratidzirwa ndiNhamba yeZveruzhinji. Kuti uone kutengesa kwako, pinda mukati uchishandisa nhamba yako yekodha, kana kuti iwe unyoresa waunoshandisa kuburikidza neimwe yemakambani eChipatimendi Chebasa. Kuti uise mutemo, taura APICMO Customer Service .

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Specifications

CAS 147804-30-6
CAS Min% 95.0
CAS Max% 98.0
MDL Nhamba MFCD07779385
InChI Key ULSBMKGFFFMGOI-UHFFFAOYSA-N
Kemikari Zita kana Nyaya ganda-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate
Infrared Spectrum zvechokwadi
Assay Percent Range 97%
Physical Form Crystalline Powder
Packaging Bhodhoro regirazi
Molecular Formula C11H19NO3
Molecular Weight (g / mol) 213.277
SMILES CC (C) (C) OC (= O) N1CCC2 (CC1) CO2
ruvara Chena
Kemikari Zita kana Nyaya Tet-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate
Melting Point 56 ° kusvika 58 ° C
Assay ≥96.0%

Tet-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Kuchengetedza uye Kugadzirisa

(147804-30-6) Tsanangudzo yenjodzi:

Zvinokonzera kutsamwa kweganda.

Zvinokonzera kusuruvara kweziso zvakakomba.

Inogona kukonzera kutsamwa kwekupemha.

Dzivisa kufema guruva / fume / gasi / mhepo / mhepo / spray.

Tet-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate Precautionary statement:

Dzivisa kufema guruva / fume / gasi / mhepo / mhepo / spray.

Pfekai magasivha ekudzivirira / zvipfeko zvinodzivirira / kudzivirirwa kweziso / kuchengetedzwa kwiso.

KANA MAMWE EYES: Isai zvakanaka nemvura kwemaminitsi akawanda. Bvisa manotsi lenzi, kana zviripo uye zviri nyore kuita. Rambai muchigadzira.

KANA UCHISHA: Bvisa mweya wakachena uye ugare wakasununguka kufema. Chengetedza yakavharwa.

Bvisa zviri mukati maro / mudziyo maererano nemitemo yemunharaunda / yeruwa / yenyika / pasi rose.

YAMBIRO: Mashoko aya anowanikwa pane iyi webhupu yakagadziridzwa maererano nemitemo yeEuropean Union (EU) uye yakarurama kune zvakanakisisa zvezivo yedu, ruzivo uye rutendo pazuva rawakabudiswa. Mashoko anopiwa anogadzirirwa chete semutungamiri wekusachengetedza nekuchengetedza zvakachengeteka. Izvo hazvifaniri kuonekwa sechirango kana kuti maitiro ehutano.

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Articles

Nafizal Hossain

Nafizal Hossain, et al. Spirocyclic compounds, zvakanyanya CCR1 antagonists.Bioorg. Med. Chem. Lett., 2013

Technical Service:

Bato revasayendisiti vane ruzivo munharaunda dzose dzekutsvakurudza kusanganisira Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical nezvimwe zvizhinji.

Tet-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Kurayira Kukuru & Kutengo:

Iwe unoda huwandu hwakawandisa nokuda kwekutsvaga kwako, kushandiswa kana kutsvakurudza zvese?


=

2 anodzokorora nokuti Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

  1. APICMO -

    An In-Depth Mharidzo ye-tert-butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)

    Isu tinogadzira uye tinogadzira Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate zvose muhuwandu uye muhuwandu hwakawanda. Pa APICMO, zvishandiso zvedu zvose zvinoteerera cGMP yehutano hwekutonga mitemo. Kana iwe uchida kutenga chinhu chikuru kana chiduku chechigadzirwa ichi, iwe uri panzvimbo yakarurama. Ingoisa urongwa kuburikidza nekubatana nevatungamiri vedu vanogamuchira uye vanogona kutarisira vatengi. Kana uchida kuwana mamwe mashoko pamusoro pechigadzirwa, ramba uchiverenga.

    Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Incazelo

    Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate inowira muboka re spiro compounds. Zvidzidzo zvinoratidza kuti inogona kuita seinhibitor ye kinases, yakadai se tyrosine. Zvadaro, zvakakonzera kushandiswa kwezvinodhaka mukurapa uye kutarisa kinase-kusanganisa kusanganisa, izvo zvinokonzera kufambira mberi kwekenza.

    Pasinei nokuva nemishonga inotengesa mishonga, chibereko chacho chinopindirana mukati mehutano hwehupenyu.

    Nhengo yakarongwa yeTert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6):

    tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

    Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Tsanangudzo

    CAS no. 147804-30-6
    Kemikari zita 1-oxa-6-azaspiro [2.5] octane-6-carboxylic acid tert-butyl ester
    Kuwanda kwevanhu (g / cm3) 1.123
    Empirical formula C11H19HERE3
    Nyaya yekubikira (˚C) 297.62
    Flash point (˚C) 133.8
    IUPAC zita Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate
    Pfungwa inoputika (˚C) 55 - 59
    Molecular weight (g / mol) 213.277
    Monoisotopic mass (g / mol) 213.136
    Chimiro chemuviri simba
    Purity 97%
    Structural formula
    Synonyms · 6- (tert-Butoxycarbonyl) -1-oxa-6-azaspiro [2.5] octane
    · 6-boc-1-oxa-6-azaspiro [2.5] octane
    · 1-oxa-6-azaspiro [2.5] octane-6-carboxylic acid tert-butyl ester
    · 1-oxa-6-azaspiro [2.5] octane-6-carboxylate
    · 1-oxa-6-azaspiro [2.5] octane-6-carboxylic acid tert-butyl ester
    · Tert-butyl-6-azaspiro [2.5] octane-1-oxa-6-carboxylate.

    Chimiro & Physical Properties yeTert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)

    Kuonekwa

    Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate ipepristini yakachena yekristini

    147804-30-6 kubatana

    Rotatable bond 2
    Hydrogen bond Mupiro wezvipo - 1 unit

    Acceptor count - 3

    Covalent 1

    147804-30-6 Computed Properties

    Name Name Property value
    XLogP3-AA 1.1
    Vapor pressure (mmHg) 0.0 ± 6
    Kusagadziriswa Bond Stereocenter Count 0
    Usingazivikanwi Atom Stereocenter Count 0
    Topological polar surface area 42.07 A ^ 2
    Refractive index 1.506
    Isotope Atom Count 0
    Heavy Atom Count 15
    Mutemo Wakafanana 0
    Misa chaiye (g / mol) 213.136
    Kunotsanangurwa Bond Stereocenter Count 0
    Kunotsanangurwa Atom Stereocenter Count 0
    Compound is Canonicalized Ehe
    Complexity 262

    Synthesis Route ye Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate

    Kune mapfumbamwe emigwagwa miviri yeiyo chigadzirwa. Pasi pane dzimwe nzira dzakakurudzirwa:

    Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

    Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

    Zvirongwa zve147804-30-6APICMO hazard icons

    • Mabasa semishonga yemishonga uye yakagadzirwa mukati
    • Inhibitor yemamwe protein kinases

    147804-30-6 Tsanangudzo Inotyisa

    • Zvichida kuvhiringidza maziso, zvichiita kuti zviparadzwe zvachose
    • Inogona kukonzera mishonga yakawanda yeganda
    • Kuvhiringidza kwemapfupa ekufema

    Zvimwe Zvokuchengetedza Kana Kubata neTert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)

    1. Kudzivirirwa Kwemunhu

    Zvidziviriro

    Iyo midziyo inofanira kunge yakafanana nemitemo yehurumende, yakadai semitemo yeEuropean Union (EU) yenyika yeEurope kana NIOSH yeUnited States. Iva nechokwadi chekudzivirirwa kwakakwana kwemuviri, meso, chiso, kupemha, uye ganda. Shandisa chero mufananidzo weN95 kana kuti tape P1 masks zvichienderana nemitemo yemunharaunda.

    Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Kuraira kwemajini

    Iva nechokwadi chokuti nzvimbo yako yekushanda inokonzera kukonzera kuputika uye kuchengeteka kwemvura.

    2. Kutanga Kubatsira Maitiro

    Kutarisa Kwameso

    Svinura maziso nemvura inonaya inotonhora kwemaminitsi anotevera 15. Wana rubatsiro rwezvehutano kana kutsamwa kuchienderera mberi.

    Ganda Kukurukurirana

    Shamba nemvura yakawandisa uye sopu yemaminitsi 15.

    Kuisa

    Rubatsiro rwekutanga runoshanda chete kana kuparara kuri kuziva. Shandisa muromo wako zvakanaka uye unwe zvinenge hafu yemvura kana mukaka. Kana munhu wacho asingazivi, awane rubatsiro rwekurumidza kune imwe nzvimbo yehupisi, a toxicologist, kana chiremba.

    Inhalation

    Tungamira munhu akabatwa mukati mekamuri yemafuro asi uchichengetedza wakasununguka. Kutarisira kupfutidza maitiro kana munhu wacho asina chaanoziva uye owana rubatsiro rwechiremba kubva kune chiremba.

    3. Kutakura Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate

    Paunenge uchishandiswa, cherechedza zvinotevera zvinodzivirira:

    • Dzivisa kufema mhepo, mhepo, mafungu, kana zvimwe zvinokonzera chepfu
    • Kupfeka zvibvumirano zvekudzivirirwa
    • Shandisa iri murabhoreti inoputika

    4. Kuchengetwa kweTert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)

    Kana isiri kushandiswa,

    • Chengeta mukati memamiriro ezvinhu akadai
    • Chengetedza chigadzirwa pasi pe nitrogen
    • Seal storage storage tightly
    • Iva nechokwadi chokuti nzvimbo yekuchengetedza inoputika, yakaoma uye inotonhorera
    • Chengetai Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate kure nevakadzika
    • Chengetedza Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate kupedza kukwanisa

    5. Mushure mekushandisa

    Mushure mekushandisa Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate,

    • Bvisa makemikari anoshandiswa kana kusvibiswa zvakakodzera
    • Shamba maoko
    • Dzorera zvakare chigadzirwa chisina kushandiswa kune chigadzirwa chepakutanga
    • Bvisa bhenji rekushanda nekuchenesa mapiritsi

    6. Fire Control

    Iva nemafungiro ekufema anozvidzivirira kuti urege kusangana nemafuta anokonzera tsvina uye mapapu, anobva pakuparara. Bvisai murazvo nemvura yakasviba, yakaoma makemikari yeupolisi, doro risingagadziriswi, kana carbon dioxide. Izvo zvinopedza mhizha zvinotarisana nehukuru hwemoto uye causative agent.

    7. Nenguva Dzakasunungurwa Maitiro

    Itai chero marwadzo kana kuputika. Shandisai spill kana kushandisa inert inobata sejecha kuti iwedzere makemikari. Bvisa muvhara rakavharwa uye ugosiya maererano nemitemo yekurasikirwa kwenharaunda yacho. Bvisa bhenji rinoshandisa uye rivhare.

    8. Stability & Reactivity yeTert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate

    Chigadzirwa chacho chakasimbiswa pasi pemamiriro ezvinhu akachengetedzwa.

    9. 147804-30-6 Kurasikirwa Kwechimiro

    Bata Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate sechinhu chakasvibiswa uye ichirasikirwa nerubatsiro rwekambani inoshandiswa yekodzero yemunharaunda.

    10. Kutumira Info

    Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) haina ngozi kune mhepo, pasi, kana kutumidzwa kwemakungwa.

    Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Ruzivo Rwekutonga

    Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) haina zvingatarisirwa kana njodzi dzinokonzerwa nezvisikwa, hutano hwevanhu, kana kuti zvakatipoteredza. zvinoramba zvichiripo kana kuti zvigadziriswa. Nekuda kwechikonzero ichi, chave chakanzi hachina ngozi uye hachina ngozi.

    Mashoko aya anoenderana nezvinodiwa munyika yose.

    Technical Details

    Masayendisiti edu vane ruzivo runobatsira muzvinhu zvehupenyu nehupenyu, shanduko yemakemikari, chromatography, makemikari yakagadzirwa, nekutsvakurudza kwesayenzi.

    Tert-butyl 1-oxa-6-azaspiro [2.5] Octane-6-carboxylate Kurayira kweBurk uye Mutengo

    Kufarira mukutsvakurudza, kubudirira, uye syntheses yemakemikari? Sarudza zvakawanda zveTert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate kubva kwatiri uye tora quotation. Taura nesu kuti tiise mutemo.

    Bibliographie

    1. National Centre For Biotechnology Information, US. National Library of Medicine, Pubchem, Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, Zvikamu 1-10.
    2. Nafizal Hossaina Svetl Ivano Jonas Bergarea Tomas Eriksson, Spirocyclic makemikari, zvikuru CCR1 vanopikisa, Bioorganic & Medicinal Chemistry Tsamba Gwaro 23, Issue 6, 15 March 2013, Mapeji 1883-1886.
    3. Ali Nasrallah Gwendal Grelier Maria Ivana Lapuh Fernando J. Duran Benjamin Darses Philippe Dauban, Dirhodium (II) -Mediated Alkene Kurwiswa neIodine (III) Oxidants, peji 12-14.
  2. Rated 5 kubva 5

    Apicmo -

    Yakanakisisa Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate nebasa randakave narina, Nice experience

Add kudzokorora

Your kero e haangazozikamwi ichibudiswa.