2-chloro-5-aminopyrimidine (56621-90-0)

Rated 5.00 Kunze kwe5 yakavakirwa 1 kasitoma Rating
(2 kasitoma wongororo)

Ichi chigadzirwa (s) chinogara pane kambani ye APICMO.

Kukwanisa kubudisa, kugadzira uye kugadzira zvakawanda zve2-chloro-5-aminopyrimidine (56621-90-0) nehutano hwehutsika pasi peCGMP
mitemo.

Category:

tsananguro

2-chloro-5-aminopyrimidine (56621-90-0) video

5-Bromopyrimidine yakashandiswa mukushandiswa kweN-heteroaryl yakashandurwa kubva kuNX -UM-arylcarbazolyl yakagadzirwa nemarladium-catalyzed aerobic uye ligand-pasina Suzuki reaction, (9- (phenylethynyl) pyrimidine) kuburikidza ne microwave yaibatsira inonzi organic synthesis (MAOS) Sonogashira protocol.

Ichi chigadzirwa (s) chinogara pane kambani ye APICMO. Kana uri kutarisa peji ino somunhu asina kubhadhara, mutengo (s) unoratidzirwa ndiNhamba yeZveruzhinji. Kuti uone kutengesa kwako, pinda mukati uchishandisa nhamba yako yekodha, kana kuti iwe unyoresa waunoshandisa kuburikidza neimwe yemakambani eChipatimendi Chebasa. Kuti uise mutemo, taura ne APICMO Customer Service.

5-Bromopyrimidine (4595-59-9) Tsanangudzo

CAS 4595-59-9
CAS Min% 97.5
CAS Max% 100.0
MDL Nhamba MFCD00006117
InChI Key GYCPLYCTMDTEPU-UHFFFAOYSA-N
Kemikari Zita kana Nyaya 5-Bromopyrimidine
Assay Percent Range 98%
Physical Form simba
Packaging Bhodhoro regirazi
Molecular Formula C4H3BrN2
Molecular Weight (g / mol) 158.986
SMILES C1 = C (C = NC = N1) Br
ruvara White-Yellow
Melting Point 69.0 ° kusvika 73.0 ° C
Assay 98%

5-Bromopyrimidine (4595-59-9) Kuchengetedza nekubataAPICMO hazard icons

(4595-59-9) Tsanangudzo yenjodzi:

  • Zvinokonzera kusuruvara kweziso zvakakomba.
  • Zvinokonzera kutsamwa kweganda.

5-Bromopyrimidine Precautionary statement:

KANA MUCHINHU KUNYARA: Shamba nesipo yakawanda nemvura.

Pfekai magasivha ekudzivirira / zvipfeko zvinodzivirira / kudzivirirwa kweziso / kuchengetedzwa kwiso.

KANA MAMWE EYES: Isai zvakanaka nemvura kwemaminitsi akawanda. Bvisa manotsi lenzi, kana zviripo uye zviri nyore kuita. Rambai muchigadzira.

YAMBIRO: Mashoko aya anowanikwa pane iyi webhupu yakagadziridzwa maererano nemitemo yeEuropean Union (EU) uye yakarurama kune zvakanakisisa zvezivo yedu, ruzivo uye rutendo pazuva rawakabudiswa. Mashoko anopiwa anogadzirirwa chete semutungamiri wekusachengetedza nekuchengetedza zvakachengeteka. Izvo hazvifaniri kuonekwa sechirango kana kuti maitiro ehutano.

5-Bromopyrimidine (4595-59-9) Nyaya

A rosuvastatin calcium tsvina mumugwagwa wepakati wakagadzirira (nekushandura kwemichina)

Chiziviso chinorondedzera nzira yekugadzirira ye rosuvastatin calcium mukati mekusachena. Nzira yekugadzirira inosanganisira: kutora formaldehyde uye [4- (4-fluorophenyl) -6-isopropyl-2- (N-methyl-methanesulfonamino) -5-pyrimidyl] triphenylphosphonium bromide sezvinhu zviduku ...

Xie Yongju; Gong Jie 2018

Technical Service:

Bato revasayendisiti vane ruzivo munharaunda dzose dzekutsvakurudza kusanganisira Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical nezvimwe zvizhinji.

5-Bromopyrimidine (4595-59-9) Kurayira Kukuru & Kutengo:

Iwe unoda huwandu hwakawandisa nokuda kwekutsvaga kwako, kushandiswa kana kutsvakurudza zvese?


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2 anodzokorora nokuti 2-chloro-5-aminopyrimidine (56621-90-0)

  1. APICMO -

    Wanga uri kutarisira huwandu hwakawanda hwe2-chloro-5-aminopyrimidine (56621-90-0)? Pano pa APICMO, tine sarudzo yakasimba kwauri. Tine nyanzvi dzine unyanzvi hwokubudisa 2-chloro-5-aminopyrimidine mudiki uye yakawanda. Zvose zvatinogadzira zvinogutsa mitemo yekugadzira yeCGMP.

    2-chloro-5-aminopyrimidine tsanangudzo

    Chloro-5-aminopyrimidine zvichida inonzi 2-chloro-5-aminopyrimidine kana 2-Chloro-pyrimidin-5-ylamine ipirrimidine ye2, chromoro-5-aminoprimidine. Pasinei nokuva nemunhu uye simba pane nguva, unofanira kungwarira paunenge uchishandisa nokuti zvinogona kukonzera kuora mwoyo uye kuputika kweganda.

    Ichi chigadzirwa chiri muboka re pyrimidines.

    Kemikari yakagadzirwa ne2-chloro-5-aminopyrimidine

    2-chloro-5-aminopyrimidine (56621-90-0)

    Synthesis routes of 2-chloro-5-aminopyrimidine

    2-chloro-5-aminopyrimidine ine maitiro maviri emigwagwa

    2-chloro-5-aminopyrimidine (56621-90-0)

    10320-42-0

    2-chloro-5-nitro ...

    2-chloro-5-aminopyrimidine (56621-90-0)

    56621-90-0

    5-amino-2-chloro ...

    2-chloro-5-aminopyrimidine (56621-90-0)

    326-19-6

    5-nitro-1H-pyrim

    2-chloro-5-aminopyrimidine (56621-90-0)

    56621-90-0

    5-amino-2-chloro ...

    2-chloro-5-aminopyrimidine (56621-90-0) zvipamberi nemiti inopedzisa

    Precursor products:

    2-chloro-5-aminopyrimidine (56621-90-0)

    2364-10-6

    2-chloro-5-aminopyrimidine (56621-90-0)

    1032-42-0

    Kuderera kwemiti:

    2-chloro-5-aminopyrimidine (56621-90-0)

    582323-10-2

    2-chloro-5-aminopyrimidine (56621-90-0)

    582323-16-8

    2-chloro-5-aminopyrimidine (56621-90-0)

    4983-28-2

    2-chloro-5-aminopyrimidine chigadzirwa chemichero

    Kemikari Name 2-chloro-5-aminopyrimidine
    IUPAC Zita 2-chloropyrimidin-5-amine
    Assay 96%
    Melting Point 198-199 ° C
    Molecular Weight 129.549g / mol.
    Molecular Formula C4H4ClN3
    Infrared Spectrum chokwadi
    Inchi 1S/C4H4ClN3/c5-4-7-1-3(6)2-8-4/h1-2H,6H2
    Inchi Key DZBKIOJXVOECRA-UHFFFAOYSA-N
    CAS Number 56621-90-0
    CAS Min 95%
    CAS Max 100%
    IUPAC Zita
    Canonical SMILES COC1 = CN = C (Cl) N = C1
    Synonyms

    1. 2-CHLORO-5-AMINOPYRIMIDINE
    2-CHLORO-5-PYRIMIDINAMINE
    2. 2-Chloropyrimidin-5-amine
    2-Chloropyrimidin-5-ylamine
    3. 2-Chloro-pyrimidin-5-ylamine
    2-CHLORO-PYRIMIDINE-5-AMINE
    4. 2-chloropyrimidine-5-ylamine
    4CH-001090
    5. 56621-90-0
    56621-90-0 5-amino-2-chloropyrimidine
    5-AMINE-2-CHLOROPYRIMIDINE
    5-amino-2-chloro pyrimidine
    6. 5-Amino-2-chloropyrimidine
    5-amino-2-chloropyrimidine, AldrichCPR
    7. 5-PYRIMIDINAMINE, 2-CHLORO-
    5-Pyrimidinamine, 2-chloro- (9CI)
    5-Pyrimidinamine, 2-chloro-
    621A900
    AB0025545
    AB1006193
    AC-4602
    8. ACMC-1AXFH
    ACT01635
    AJ-77115
    AK-24171
    AKOS006280308
    AM20100394
    AN-11808
    ANW-32561
    AX8002227
    BCP23418
    BR-24171
    C-01240
    C-1663
    CA0100
    CA-1644
    CC-21115
    CJ-16669
    CS-W005338
    CTK5A5459
    DB-010236
    DTXSID60480849
    DZBKIOJXVOECRA-UHFFFAOYSA-N
    FCH836002
    FT-0640401
    HC210150
    HP21136
    KB-169841
    KB-23304
    KS-0000037F
    LS20481
    MFCD06412560
    MolPort-000-140-202
    OR30541
    PB21893
    PS-4730
    PubChem6963
    9. Q-102843
    QC-1705
    RP00932
    SBB051953
    SC-05394
    SCHEMBL40450
    ST1141034
    SY013941
    TC-067988
    TL8003661
    TRA0015152
    VP50264
    W7026
    WT624
    ZINC20357595
    ZX-AT005418

    Makemikari uye zvinhu zvemukati 2-chloro-5-aminopyrimidine

    Kuonekwa:

    2-chloro-5-aminopyrimidine iripo semupfu tsvuku.

    Kushamwaridzana:

    Covalent bonds count 1 unit
    Zvinotenderera zvisungo kuverenga hapana
    Hydrogen bonds Donor-1unit
    Acceptor-3 diyuniti

    Computed properties of 2-chloro-5-aminopyrimidine

    Zita renzvimbo yacho ukoshi
    Nhamba ye isotope atomu 0
    Inonyatsotsanangurwa nhengo yeboka 0
    Sttereocenter isina kufungidzirwa kuverengwa kwehurumende 0
    Wakazvidzivirira akatsunga atomu kuverenga 0
    Munhu asina hanya asina kufanirwa atom count. 0
    Nhamba yeatomu yakaoma 8
    XLogP3-AA 0.5
    Mutemo Wakafanana 0
    Icho chinokonzerwa kanononi Ehe
    Zvakakwana masasa 129.009 g / mol.
    Mon isotopic mass 129.009 g / mol.
    Pamusoro peti topological polar 51.8 A ^ 2
    CACTVS shanduro yezvinyorwa zvidhi AAADcYBjAAAAAAAAAAAAAAAAAAAAA
    AAAAAAAAAAAAAAAAgAAAHAIQAAAA
    CAjBEgQt0JZIEACgABRnZACAgCkREqABU
    CAodBCASIBASUAUBAgIEAJAACAAAAAAAA
    AAAAAAAAAAAAAAAAAAAAAAAAAAAA ==
    Complexity 69.7

    Uses of 2-chloro-5-aminopyrimidine

    2-chloro-5-aminopyrimidine inobatsira mukutsvakurudza, kubudirira uye chigadzirwa synthesis.

    Kudzivirirwa kwekutora mukubata 2-chloro-5-aminopyrimidine

    Paunenge uchishanda ne2-chloro-5-aminopyrimidine yekutsvakurudza, kukurudzirwa kana chigadzirwa, iwe unofanirwa kutarisira. Izvi ndezvokuti mugumisiro unogona kuva nemigumisiro inokuvadza pahutano hwako kana uchinjwa. Izvo zvinotevera ruzivo rwakakwana pamusoro pekuchengetedza matanho ekufungisisa paunenge uchishanda ne2-chloro-5-aminopyrimidine.

    2-chloro-5-aminopyrimidine yakaenzana nenjodzi.APICMO hazard icons

    • Chigadzirwa chacho chinokuvadza pakuputika.
    • Zvinokuvadza meso zvinokonzera kutsamwa kukuru kweziso.
    • Ichi chigadzirwa chinogona kukonzera kusafema.
    • Inokuvadza pakupinza.
    • Izvozvo zvinogona kuguma neganda remhepo.

    Zvishandiso zvekudzivirira pachedu

    Paunenge uchishanda ne7-Benzyloxy-4-chloro-6-methoxyquinazoline (162364-72-9), zvinokosha kudzivirira ganda rako, maziso pamwe chete nehutano hwemapfupa uchishandisa zvombo zvekuchengetedza. Izvi zvinoita kuti muviri wako uchengeteke kubva kune ngozi dzakanyorwa.

    Kuchengetedzwa kweganda

    • Ita zvekusachengetedzwa kusachengetedzwa.
    • Iva nechokwadi chokuti zvipfeko ndezvenguva refu kuti zvifukidze muviri wako wose.
    • Magirafu anodikanwa kuvhara maoko ako.

    Ziso uye zviso zvekudzivirira

    • Bhara maziso ako nekuchengetedza magogo.
    • Izvo zvinogadziriswa zvingave zvakagadzirwa nechokudzivirira nhoo yekufukidza chiso.

    Kudzivirira kupora

    Pasi pemamiriro ezvinhu akadai, kuchengetedzwa kwekufema kunogona kunge kusingadiwi. Zvisinei, usapinda mumhepo, guruva, mhepo, magasi kana spray. Zvirwere zvinoputika zvinogona kuchengetwa zvakagadzirira zvinokurumidza.

    7-Benzyloxy-4-chloro-6-methoxyquinazoline (162364-72-9) kuchengetedza

    1. Engineer control

    Iro laboratori inofanira kuva nemhepo yakakwana kana kuti kushanda kunze.

    2. 7-Benzyloxy-4-chloro-6-methoxyquinazoline (162364-72-9) handling

    Kana iri kushandiswa:

    • Usashandisa chigadzirwa usati wawana mirayiridzo yakakodzera.
    • Verenga uye unzwisise mirairo inopiwa
    • Kupfeka zvombo zvekuchengetedza uye zvipfeko.
    • Usasunungura chigadzirwa mumhepo.
    • Dzivisa kusvuta, kutora zvinwiwa kana zvokudya kana uchishanda nemakemikari.
    • Usapisa chigadzirwa.
    • Dzivisa kugaya kana kuisa mishonga yemakemikari.
    • Dzivisa kushanda pamwe nemakemikari paunenge uri pamuviri kana panguva yekurapa.
    • Usapisa kemikari pasi pekuvharirwa.

    Mushure mekushandisa

    • Chengetedza chigadzirwa chisina kushandiswa mubhodhoro rekuchengetedza uye urivhare.
    • Unganidzai madota uye makani asina chinhu uye muatakure ivo kuti varege. Izvo zvinhu zvinoshandiswa zvinoshandiswa kunyorwa uye zvakakiyiwa.
    • Bvisa nguo dzakasvibiswa.
    • Usatora mbatya dzakasvibiswa kubva kubasa kana kuti ushandise zvakare vasati vashamba.
    • Bvisa magirafu zvakanyatsonaka uye uzvichengete zvakanaka sezvinodiwa nematare ehurumende kana emunharaunda.
    • Bvisa bhenji rekushanda uye ugeze.
    • Shamba chiso chako nemaoko zvakakwana nemvura yakakwana yechando.

    3. Kuchengetedza zviyero zve 7-Benzyloxy-4-chloro-6-methoxyquinazoline (162364-72-9)

    Apo 7-Benzyloxy-4-chloro-6-methoxyquinazoline (162364-72-9) isiri kushandiswa, iva nechokwadi chokuti iwe uchengetedze kemikemikari pasi pemamiriro anotevera.

    • Nguva dzose shandisa chigadziko chepakutanga kuchengetedza makemikari uye cork iyo zvakasimba
    • Nyora bhodhoro zvakakodzera.
    • Ramba uri kure nekusvika kwevanhu vasingabvumirwi nevana.
    • Inzvimbo yekuchengetedza inofanira kuva nehuwandu hwemhepo yakachena.
    • Chengeta makemikari kunze kwezuva rakananga uye kupisa.

    4. Matambudziko ekutanga

    Zviitiko zvinowanzoitika zvinogona kuitika chero nguva yaunoshanda na2-chloro-5-aminopyrimidine. Kutsvaga kurapwa kana zviitiko izvi zvikakosha. Sezvo ma medichi angasawanika pakarepo, zvakakosha kugovera mazano ekutanga anotevera kune avo vakaurayiwa vasati vauya kuna vanachiremba.

    Mukana wekugadza:

    • Shandisa mvura yakawanda inotonhora kuti usuke muromo.
    • Kana munhu wacho asina chaanoziva, usatora chero chinhu kuburikidza nemuromo.
    • Shanya kana kukoka mishonga rubatsiro.

    Mukana wekudzivirira mukati memakemikari:

    • Tambanudza kuurayiwa panze kana kune imwe nzvimbo ine nzvimbo yakakwana yekuputika.
    • Dana mishonga yekuwedzera kurapwa.

    Paunenge uine maziso:

    • Shamba maziso nemvura zhinji inotonhorera.
    • Bvisa ziso rekuona lens kana iwe unazvo.
    • Ramba uchigunzva maziso kwemaminitsi gumi.
    • Kana mukaramba mukutsamwa, bvunza chiremba.

    Paunosangana nekanda

    • Bvisai zvinyorwa kubva panzvimbo yekutaurirana.
    • Geza nzvimbo yakakanganiswa kwemaminitsi e15 nemvura inotonhorera uye sese yakakwana.

    5. Zvichida kuparadzanisa zviyero

    Shandisa jecha kana vermiculite kuti uwane zvinoshandiswa. Isa pakaputika muzvikwata zvakakodzera kuti urege.

    6. Kupisa moto

    2-chloro-5-aminopyrimidine kana kuti iyo inogona kuunza moto. Kana izvi zvikaitika pangozi, zvinotevera ndezvokuchengetedza kwaunofanira kufungidzira. Shandisa mutezo wepolym, doro risingakwaniki, yakaoma makemikari kana carbon dioxide kuti udzimure moto. Kana zvikaputika, rega kurwisa moto uye ugobuda munzvimbo yacho. Kupfeka zvipfeko zvekuchengeteka uye zvipfeko paunodzima moto.

    7. 2-chloro-5-aminopyrimidine maringe matsvudzo

    2-chloro-5-aminopyrimidine haisi nengozi yekutakura pasi uye kumhepo.

    8. Kurambidzwa kwemarara

    Unganidza matongo uye uronge semarara chaiwo akagadzirirwa kurasa. Pamusoro pemarara kune kambani inoshandiswa kurasa tsvina.Handle tsvina maererano nemitemo yehurumende, yenyika kana yemunharaunda pamusoro pekurasa marara.

    9. 2-chloro-5-aminopyrimidinereactivity uye kugadzikana

    Pasi pemamiriro ezvinhu akachengetwa akachengetwa, chigadzirwa chacho chakasimba.

    Chigadzirwa chacho hachifaniri kujekeswa kune zvakasimba mashizha kana acid.

    Kupisa kwe2-chloro-5-aminopyrimidine inobereka carbon chloride, carbon oxides, uye nitrogen oksijeni.

    Information regulatory

    2-chloro-5-aminopyrimidine chigadzirwa chinoshandiswa mukutsvakurudza uye kubudirira; naizvozvo hazvisi zvekushandisa kwevanhu kana zvemhuka. Chigadzirwa chacho chinofanira kutarisirwa uye kuchengetwa pasi pemitemo yakarongedzwa. Inofanira kurapwa nevashandi vakarovedzwa vane unyanzvi mura laboratory. Izvi zvinofanira kuva pasi pekuongororwa kwevatariri vanozivikanwa.

    Technical service

    Iwe unogona kuva nechokwadi chezvigadzirwa zvemhando uye maitirwo kubva kwatiri pa APICMO. Izvi ndezvokuti tine boka reongororo rakapiwa mukurudziro nekutsvakurudza mune zvakasiyana-siyana zveminda kunosanganisira chromatography, chemakemikari yesayenzi, hupenyu sayenzi kuongorora sayenzi nevamwe.

    2-chloro-5-aminopyrimidine kurongedza kukuru uye mutengo

    Iwe unoshaya 2-chloro-5-aminopyrimidine mune zvakawanda zvakakura nokuda kwekutsvaga kwako, tsvakurudzo kana chigadzirwa chekutanga? Usazeza; Dhipatimendi redu rekuchengetedza vatengi rakagara rakagadzirira kukuteererai. Taura nesu uye ita mirairo yako.

    Bibliography:

    1. National Center for Biotechnology Information, US National Library of Medicine, Pubchem, 2-chloro-5-aminopyrimidine, Zvikamu 1-9.Pathway Therapeutics Limited Patent: US2011 / 9405 A1, 2011; Nzvimbo yepa patent: Peji / Peji peji 56;
    2. Desmond J. Brown, John Wiley & Vanakomana, 15 Sep 2009, The Pyrimidines, peji 153,167,316,469, 503.
    3. Robert Cooley ElderfieldWiley, 1957 - Heterocyclic makundi, peji 206, 270, 305.

  2. Rated 5 kubva 5

    Apicmo -

    Yakanakisisa 2-chloro-5-aminopyrimidine uye basa randakave narina, Nice experience

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