(S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3)

(2 kasitoma wongororo)

Ichi chigadzirwa (s) chinogara pane kambani ye APICMO.

Kukwanisa kubudisa, kugadzira uye kugadzira zvakawanda zve (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) nehutano hwehutsika pasi peCGMP
mitemo.

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tsananguro

(S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) - APICMO video

(S) - (-) - 2-Methyl-2-propanesulfinamide, CAS 343338-28-3, inogona kushandiswa kukudziridza benzofuran-based farnesyltransferase inhibitors sevanopesana nekenza.Iyo inogonawo kushandiswa (20E) N- [t-butyl- (S) -sulfinyl] -3β- (t-butyldimethylsilyloxy) -pregn-5-en-20-imine, iri pakati pomugadziri wevanopikisa uyerogen receptor.

(S) - (-) - 2-Methyl-2-propanesulfinamide inogona kushandurwa nyore nyore kuva P, N-sulphinyl imine ligands kuburikidza nekugadziriswa nealdehydes uye ketone, iyo inogona kuwanikwa iridium-inogadziriswa seyomutengo hydrogenation yeolefins.

Chiral auxiliary inoshandiswa mukugadziriswa kwe trifluoroethylamines nekushandurwa kwe trifluoroacetaldehyde kune chiral imine yakateverwa nehutano ne aryl lithium uye acidic methanolysis.

(S) - (-) - 2-Methyl-2-propanesulfinamide inoshandiswa mukuita. Inoshandiswawo se reagent yekugadzira chiral amines. Inobatsira sechiral anobatsira inoshandiswa kushandiswa kwetatu trifluoroethylamines nekushandurwa kwe trifluoroacetaldehyde kune chiral imine. Iyo inobatanidzwawo mukushandurwa kweP, N-sulphinyl imine ligands kuburikidza nekugadziriswa nealdehydes ne ketone, iyo inogona kuwanikwa iridium-inogadziriswa seyakakwana hydrogenation yeolefins. Uyezve, inoshanda sechirongwa chekugadzirira kwemakemikari nemishonga inoshandiswa kwemishonga.

Ichi chigadzirwa (s) chinogara pane kambani ye APICMO. Kana uri kutarisa peji ino somunhu asina kubhadhara, mutengo (s) unoratidzirwa ndiNhamba yeZveruzhinji. Kuti uone kutengesa kwako, pinda mukati uchishandisa nhamba yako yekodha, kana kuti iwe unyoresa waunoshandisa kuburikidza neimwe yemakambani eChipatimendi Chebasa. Kuti uise mutemo, taura ne APICMO Customer Service.

(S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3) Specifications

CAS 343338-28-3
CAS Min% 95%
CAS Max% 100%
MDL Nhamba MFCD05861480
InChI Key CESUXLKAADQNTB-ZETCQYMHSA-N
Kemikari Zita kana Nyaya (S) - (-) - 2-Methyl-2-propanesulfinamide
Infrared Spectrum zvechokwadi
Physical Form rakasimba
Packaging Bhodhoro regirazi
Molecular Formula C4H11NOS
Molecular Weight (g / mol) 121.20
SMILES
ruvara Yakachena kusvika pane-chena
Melting Point 97-101 ° C
Assay 97%

(S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) Kuchengetedza nekubataAPICMO hazard icons

(343338-28-3) GHS H Nyaya

  • Inokuvadza kana ikamedzwa
  • Zvinokonzera kutsamwa kweganda
  • Zvinokonzera kusuruvara kweziso zvakakomba
  • Inogona kukonzera kutsamwa kwekupemha

(S) - (-) - 2-Methyl-2-propanesulfinamide GHS P Zvinyorwa

  • Dzivisa kufema guruva / fume / gasi / mhepo / mhepo / spray.
  • Shamba ... zvakakwana mushure mokubata.
  • Usadya, kunwa kana kusvuta kana uchishandisa chigadzirwa ichi.
  • Shandisai kunze kunze kana mune nzvimbo yakanaka.
  • KANA AKASIMBA: Bvunza CENTER POISON kana chiremba

YAMBIRO: Mashoko aya anowanikwa pane iyi webhupu yakagadziridzwa maererano nemitemo yeEuropean Union (EU) uye yakarurama kune zvakanakisisa zvezivo yedu, ruzivo uye rutendo pazuva rawakabudiswa. Mashoko anopiwa anogadzirirwa chete semutungamiri wekusachengetedza nekuchengetedza zvakachengeteka. Izvo hazvifaniri kuonekwa sechirango kana kuti maitiro ehutano.

(S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3) Articles

Mechanochemical synthesis yeN-tert-butanesulfinyl imines pasi pemamiriro esimbi asingasviki

Iyo iri nyore uye inoyevedza mechanochemical nzira yekubvumira kwealdehydes ne tert-butanesulfinamide vachishandisa catalytic yakawanda yeodhidhi pasi pesimbi- uye isina kushandiswa-pasina mamiriro ezvinhu inotsanangurwa.

Tetrahedron 2018 vol. 74 # 25 p. 3101 - 3106

Nzira Yakakosha uye Inobatsira yeEnantioselective Synthesis yeTemtiary Trifluoromethyl Carbinols

An sulfinamide / olefin yakagadzirwa chiral ligand, MetSulfolefin, yakagadzirwa nokuda kweanantioselecting rhodium-catalysed kuwedzera kwe aryl-boronic acid ku trifluoromethyl ketones. Iri rakafu-rakagadzikana ligand harifariri mweya, oksijeni uye unyoro, uye inowanikwa mumatanho maviri akareba anobvumira kunotengeswa kusina kutengeswa (R) -tert-butanesulfinamide.

Advanced Synthesis uye Catalysis 2018 vol. 360 # 6 p. 1273 - 1279

Technical Service:

Bato revasayendisiti vane ruzivo munharaunda dzose dzekutsvakurudza kusanganisira Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical nezvimwe zvizhinji.

(S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) Kurayira kweBurk & Mutengo:

Iwe unoda huwandu hwakawandisa nokuda kwekutsvaga kwako, kushandiswa kana kutsvakurudza zvese?


=

2 anodzokorora nokuti (S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3)

  1. APICMO -

    Isu tinobudisa (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) yakawanda pasi pe cGMP yokugadzira mitemo. Ichi chigadzirwa chinowanikwa pane kambani ye APICMO. Icho chinogadzirirwa chemakemikari yakashandiswa, tsvakurudzo, nekugadzirwa kwezvinangwa.

    Chimiro chemakemikari (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3):

    (S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3)

    About (S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3)

    (S) - (-) - 2-Methyl-2-propanesulfinamide chimiro chechiral, icho chinowira mune imwechete sulphonamides, zvivako zvekuvakira, uye chiral mishonga.

    Ichi chigadzirwa chinoshandiswa zvakasiyana siyana kusanganisira kuita seanopesana nekenza agent. Muchidzidzo chekurapa kwekenza, inobatsira mukudziridza inhibitor ye benzofuran-based farnesyltransferase. Kunze kwekuti, inoshanda sepakati pekugadzirira (20E) -N- [t-butyl- (S) -sulfinyl] -3β- (t-butyldimethylsilyloxy) -pregn-5-en-20-imine, anonyanya kupikisa we androgen receptors.

    Iyo inogadziriswa ne ketoni uye aldehydes kuburikidza ne iridium-inokonzerwa nemafuta olefins hydrogenation, i (S) - (-) - 2-Methyl-2-propanesulfinamide inoshandura mu P, N-sulfinyl imine ligands.

    Paunogadzira trifluoroethylamines, (S) - (-) - 2-Methyl-2-propanesulfinamide inoshanda sechiral anobatsira. Chibereko chacho chinoshandura trifluoroacetaldehyde kune chiral imine, vasati vabata ne acidic methanolysis uye aryl lithium.

    Zvishandiswa zve (S) - (-) - 2-Methyl-2-propanesulfinamide

    • Synthesis ye chiral amines
    • Icho chiri mubatsiri wechiral mune zvisinganzwisisiki synthesis ye trifluoroethylamines
    • Kemikari nemishonga inopindirana
    • Kuchinja P, N-sulphinyl imine ligands kuburikidza nekuvhenekera kweketone nemagetsi, nokuda kweanomine olefin hydrogenation

    343338-28-3 Product Specifications

    Nyaya yekubikira (˚C) 200.6
    Canonical SMILES CC (C) (C) S (= O) N
    CAS no. 343338-28-3
    Kemikari zita (S) - (-) - 2-Methyl-2-propanesulfinamide
    Kuwanda kwevanhu (g / cm3) 1.044
    Flash point (˚C) 75.1
    Hill notation C4H11NOS
    IUPAC zita 2-methylpropane-2-sulfinamide
    Pfungwa inoputika (˚C) 97 - 101
    Molecular weight (g / mol) 121.2
    Monoisotopic mass (g / mol) 121.056
    Chimiro chemuviri simba
    Purity 97%
    Synonyms · (S) -tert-butanesulfinamide
    · (S) -2-methylpropane-2-sulfinamide
    · S-tert-butylsulfinamide
    · (S) -t-butyl sulfinamide
    · (S) - (-) - tert-butanesulfinamide
    · (S) -2-methyl-2-propanesulfinamide
    · (S) -2-methyl-propane-2-sulfinic acid amide

    Physical & Chemical Properties of (S) - (-) - 2-Methyl-2-propanesulfinamide

    Kuonekwa

    (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) isiri-chena cristalline powder.

    Kubatanidza (S) - (-) - 2-Methyl-2-propanesulfinamide

    Hydrogen bond Mupiro wezvipo - 1
    Acceptor count - 3 units
    Covalent 1
    Rotatable bond 1

    (S) - (-) - 2-Methyl-2-propanesulfinamide Computed Properties

    Name Name Property value
    XlogP3-AA 0
    Vapor pressure (mmHg) 0.116
    Kusagadziriswa Bond Stereocenter Count 0
    Usingazivikanwi Atom Stereocenter Count 0
    Topological polar surface area 62.3 A ^ 2
    Surface mhirizhonga (dyne / cm) 49.8
    Refractive index 1.493
    Isotope Atom Count 0
    Heavy Atom Count 7
    Mutemo Wakafanana 0
    Misa chaiye (g / mol) 121.056
    Enthalpy of vaporization 45.64 kJ / mol
    Kunotsanangurwa Bond Stereocenter Count 0
    Kunotsanangurwa Atom Stereocenter Count 1
    Compound is Canonicalized chokwadi
    Complexity 84.2

    The Synthesis Routes of (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3)

    (S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3)

    The Downstream and Precursor Products of (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3)

    Kuderera

    (S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3)

    Precursors

    (S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3)

    (S) - (-) - 2-Methyl-2-propanesulfinamide GHS Hazard Statements

    (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) inogumbura. Apo inopinda mumuviri, inokonzera kushushikana kwehutano uye kupisa kweganda. Izvo zvinogumburawo meso nemukana wekuparadzwa kweziso rekupedzisira. Kana ikamedzwa, inokuvadza uye inoda kurapwa kwenguva pfupi.

    Zvokuchengetedza Zvidzidzo pakushandisa (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3)

    1. Kubata (S) - (-) - 2-Methyl-2-propanesulfinamide

    Usashandisa (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) kunze kwekuti iwe une ruzivo kushandisa chemishonga inokuvadza kana uri pasi pekuchengetedzwa kwakasimba neunyanzvi.

    Precautionary Statements

    Dzivisa kuvhiringidza mhepo yakasunungurwa, mafesi, uye magesi. Nzira yakarurama yekudzivisa kufema mumhepo inotyisa yakasvibiswa nemhepo iri kuburikidza nekugadzirisa kwekudzima kwemazuva ekunze uye kuisa kune chinogamuchirwa chine mweya. Dzivisa kushandisa mutauro wezvokudya kana zvinwiwa, kuti urege kuvhara chemakemikari. Zvimwe, s (-) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) mumoto wemoto, kunze, kana nzvimbo yakanaka.

    Engineering Controls

    Isai fume mumba ma laboratory yako. Kuchenesa mhepo uye kupedza kuputika kwemhepo kuchachenesa mhepo uye kutungamira tsvina yemhepo kubva kure nemushandisi. Funga kuisa bhati rakanaka rokusvinura uye kuchengeteka.

    Kudzivirirwa Kwemunhu

    Shandisa maziso akavhara maziso, shangu dzerabha, mafiritsi ekuputira, mask mashizha, uye makemikari asingadziviriri. Endai mufananidzo weN95 uye faira P1 midziyo, maererano neU.S. uye yeEurope (EN143) mitemo, maererano.

    2. Mushure mekushandisa

    Mushure mekushandisa (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3), bvisa magasi akasvibiswa. Ramba magirafu semakemikari uye ushambidze zvipfeko usati washandisa zvakare. Chero chemakemikari isina kufanirwa inofanira kudzorerwa kunzvimbo yekuchengetedza yekutanga uye yakavharwa.

    3. Kuchengetedza (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3)

    Iyo yakakwana yekuchengetedza kwekuchengetedza haifaniri kuva yakawanda kupfuura 8 ° C. Chinhu chipi nechipi chinokosha ichi chichaita kuti chigadzirwa chisagadzikane. Iva nechokwadi chokuti bhokisi racho rakanyatsonyorwa, rakasimbiswa, uye rakachengetwa munzvimbo yakachengeteka.

    Chengetai (S) - (-) - 2-Methyl-2-propanesulfinamide kure nemirazvo, kupisa, kana mashizha ane simba. Pasi pemamiriro ezvinhu aya, chibereko chacho chinokurumidza kuparara, kuchinja zvinhu zvinokuvadza.

    4. Kutanga Kubatsira Maitiro

    Mhinduro idzi dzekukurumidzira hazvirevi kurapwa kwekupedzisira kwekutarisira mamiriro ezvinhu ane ngozi (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3). Haisi kutsiva kurapa kana kutarisira ngozi dzechigadzirwa. Saka, edza kuonana nechiremba kana iwe uchiramba uchinzwa usina kunetseka. Matambudziko akadai zvakadai sekufema kunetseka uye chepfu muhutachiwana hunogona kudiwa nokukurumidza kubva kune imwe nyanzvi yezvokurapa.

    Kuisa

    Tanga nekushambidza muromo nemvura yakakwana, uye utore kusvika mumakumbo matatu emvura kana mukaka. Kana iwe usingakwanisi kuchengeta chero shanduko, enda kune imwe nzvimbo yehupfu kana chiremba.

    Inhalation

    Tungamira munhu kune nzvimbo inoputika. Iva nechokwadi chokuti nzvimbo yacho yakanyatsogadzikana kuti iite kuti kufema. Iwe unogona kutora kupfutira maitiro kana kupfuvara kunopera.

    Mutumbi Wekubatana

    Eyes

    Shenesa ziso nekuparadzanisa eyelidhi yepamusoro kubva kumucheto uchishandisa minwe. Chengetedza maziso akasvinura uye shandisa mvura yakachena inotonhora mvura.

    ganda

    Bvisa uye ugeze zvipfeko zvakasvibiswa pakarepo. Nyatsoridza ganda nesipo uye mvura yakawanda yemvura inenge isingapfuuri nemaminitsi 10.

    5. Nenguva Dzakasunungurwa Maitiro

    Hapana kuvuza kana kuputika kunofanira kubudiswa kune zvakatipoteredza. Kunze kusina husi hwakasimba, simudza mvura yakasvibiswa nezvinhu zvakanyanyisa sejecha. Chengetedza zvinhu zvose mumunyoro wakanyora musati watora semidziyo yakakosha.

    6. Zvinotisa Moto

    Zvidzivirire pamhepo inogona kukuvadza nekuisa mishonga yekufema zvakanaka. Kuchenesa moto uchishandisa carbon dioxide, doro risingadziviriri, kupisa mvura, kana kuti yakaoma makemikari powder.

    7. Incompatibilities of (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3)

    Chigadzirwa chacho hachigadzikani kana chichiiswa mumoto, kupisa, kutonhora kwakanyanya, uye mishonga yakasimba. Mamiriro akadaro anokonzera kuparara kwe (S) - (-) - 2-Methyl-2-propanesulfinamide mu carbon (II) oxide, oksijeni ye nitrogen, uye sulfur oxidhi; izvo zvose, zvinokuvadza kana ukafema.

    8. 343338-28-3 Kurasikirwa Kwechimiro

    Dzinga (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3) sechinhu chakasvibiswa. Kuti zvive nyore, tora rubatsiro kubva kune imwe kambani inoshandiswa pakuderedza kusvibisa pedyo newe. Kana iwe uri wekushandisa makemikari wenguva dzose, ichava mari yakawanda uye iri nyore kuisa kemikisitiri incinerator yekuparadza madhara ane ngozi.

    9. Kutumira Mashoko

    (S) - (-) - 2-Methyl-2-propanesulfinamide yakachengeteka yekutakura nzira dzose kusanganisira pasi, mhepo, uye marita.

    Regulatory Info

    Iva nechokwadi chekutevera chero mitemo, mitemo, nemitemo inotungamirira kushandiswa kwe (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3).

    Technical Details

    Pa APICMO, tinokudzwa kuva nesangano rezvesayenzi rakakosha mune zvepanyama uye hupenyu hwehupenyu, makemikari synthesis, chromatography, kuongorora makemikari, uye tsvakurudzo inobatsira inobatsira.

    Kurongeka kweBurk uye Mutengo we (S) - (-) - 2-Methyl-2-propanesulfinamide (343338-28-3)

    Iwe uri nyanzvi yezvekutsvakurudza inotsvaka zvakawanda zve (S) - (-) - 2-Methyl-2-propanesulfinamide nokuda kwekushandiswa kwako kana maitiro ekurapa mishonga here? Tarisa mukati medu kune imwe yakachena michina yemiti. Zviwanire iwe kambani, tarisa huwandu, uye taurirana nevatengi vedu vanotarisira kuchengetedza.

    Bibliographie

    1. National Centre For Biotechnology Information, US. National Library Of Medicine, PubChem, (S) - (-) - 2-Methyl-2-propanesulfinamide, Zvikamu 1-9.
    2. Kumar Gadamasetti, Tamim Braish, CRC Press, 10 Dec 2007, Science, Process Chemistry muDhipatimendi reMishonga, Bhuku 2: Matambudziko muAdam Ever Change Climate, peji 34-36.
    3. JOHN WILEY & SONS INC, John Wiley & Vanakomana, 13 Jul 2015, Science, Organic Syntheses: Collective, Volume 11, peji 45-49.

  2. Apicmo -

    Yakanakisisa (S) - (-) - 2-Methyl-2-propanesulfinamide nebasa randakave narina, Nice experience

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