Blog

Zhaosen Zeng Ph.D. chidimbu chehumbowo chemamiriro efundo ne kodzero

Zhaosen Zeng Ph.D. chidimbu chehumbowo chemamiriro efundo ne kodzero

Maitiro makuru

Inyanzvi dzakanaka mumunda wehutano hwehutachiona hwemakemikari, hwakasimba mukushandiswa kwesanganiswa reagents uye unyanzvi huri muruoko rwekushandiswa kwe benzonitrile, phenol, naphthol, coumarin, thiocoumarin, quinoline, quinozoline, pyrimidine, pyridine, indole, indazole, Imidazole uye benzimidazole annulated heterocycles.
Zvinhu zvakasikwa mukugadzirisa matambudziko: Kuvandudza nzira itsva dzekugadzira maitiro / nzira yehutano muhutano hwemakemikari akawanda.

dzidzo

  • 2006.9-2011.1 Ph.D. kuFudan University (China) neProf. (Dr.) Fener Chen. Specialization in Organic Chemistry.
    "Ongororo yeChina-nucleoside HIV Reverse Transcriptase Inhibitors I: Kugadzira, Synthesis uye SAR Tsvakurudzo yeHybrid DABP Analogues II: Kugadzirisa, Synthesis uye SAR Tsvakurudzo yeC2-DAPY Analogues"
  • 9-2006.6 Mudzidzisi weSayenzi muKemistri kuXuzhou Normal University (China)
    Specialization in Organic Chemistry. Chirongwa chekutsvakurudza pasi pekutarisa kwaProf. Xiangshan Wang.
    "Studies on the Applications of KF-Al2O3 mu Organic Synthesis"

Dzidzo yeUnyanzvi

  • Kugadziriswa kwemhepo inoshandiswa nezvinhu zvinoshandisa shanduro yeSchlenk, high vacuum uye glove box techniques.
  • Synthesis uye maitiro ekugadzirwa kwehupenyu uye organometallic makemikari anoshandisa nzira dzinowanzobatwa nemabhenji (Multi-step synthesis, purification uye analytical techniques, HPLC, GC).
  • Synthesis of catalysts (1st uye 2nd generation Grubbs) uye vari pakati nepakati (carbeneligands).
  • Simba rekuongorora uye kuronga zvinhu zvakawanda zvezvinhu zvakasikwa zvinobva pane
    Disconnection approach.
  • Unyanzvi mune zvinyorwa zvepuraneti (eg EndNote, Word, Excel, Power Point) uye zvakasiyana-siyana zvemakemikari anowanzoenderana nedatabases (eg ChemDraw, Isis, SciFinder, Beilstein MDL CrossFire)

Publications

1. Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Lead Optimization of Diarylpyrimidines seInhibitors yeChina-non-nucleoside HIV-1 Reverse Transcriptase, ChemMedChem 2010, 5 , 837-840.

2. Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Evan De Clercq, Jan Balzarini, Christophe Pannecouque, Hybrid Diarylbenzopyrimidine Asina Nucleoside Reverse Transcriptase Inhibitors seNyika Yakapikirwa Inotungamirira Anti -HIV-1 Chemotherapy, Bioorg. Med. Chem. 2010, 18, 5039-5047.

3. Xiao-Qing Feng, Yong-Hong Liang, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Maitiro Akashandurwa eDAPY Analogues neAntiv anti-HIV-1 Activity, ChemMedChem 2009, 4, 219 -224.

4. Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Design, Synthesis, uye SAR yeNaphthyl-Substituted Diarylpyrimidines seNi-Nucleoside Inhibitors yeHIV -1 Reverse Transcriptase, ChemMedChem 2009, 4, 1537-1545.

5. Xiao-Qing Feng, Zhao-Sen Zeng, Yong-Hong Liang, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Synthesis uye Biological Kuongororwa kwe4- (hydroxyimino) arylmethyl diarylpyrimidine yakafanana seNogona Nucleoside Reverse Transcriptase Inhibitors pamusoro peHIV. Bioorg. Med. Chem. 2010, 18, 2370-2374

6. Xiang-Shan Wang, Zhao-Sen Zeng, Da-Qing Shi, Xian-Yong Wei uye Zhi-Min Zong. Chimwe chekutanga-2-amino-3-cyano-4-aryl-1,4,5, 6-tetrahydropyrano [3,2-c] quinolin- 5-imwe yakagadzirwa kushandisa KF-Al2O3 sechinhu chinokonzera [J]. Synth. Commun., 2004, 34 (16): 3021 ~ 3027.

7. Xiang-Shan Wang, Zhao-Sen Zeng, Da-Qing Shi, Xian-Yong Wei uye Zhi-Min Zong. Kushandiswa kwepachiyero kwe2-amino-3-cyano-4-aryl-1,4,5,6 -tetrahydrobenzo [h] chromenes inogadzirwa achishandisa KF-Al2O3 sechinhu chinokonzera [J]. Synth. Commun., 2004, 34 (18): 3265 ~ 3271.

8. Xiang-Shan Wang, Zhao-Sen Zeng, Da-Qing Shi, Xian-Yong Wei uye Zhi-Min Zong. KF-alumina yakagadzirisa imwe pikari synthesis ye pyrido [2,3-d] pyrimidine zvigadzirwa [J]. Synth. Commun., 2004, 34 (23), 4331 ~ 4338.

9. Xiang-Shan Wang, Zhao-Sen Zeng, Da-Qing Shi, Shu-Jiang Tu, Xian-Yong Wei uye Zhi-Min Zong. Nhatu-chikamu, imwe-pot synthesis ye pyrido [2,3-d] pyrimidine Derivatives inoshandiswa neKF-alumina [J]. Synth. Commun., 2005, 35: 1921 ~ 1927.

10. Xiang-Shan Wang, Zhao-Sen Zeng, Yu-Ling Li, Da-Qing Shi, Xian-Yong Wei uye Zhi-Min Zong. Nyore nzira yekufananidza arylmethylenemalononitrile pasina chekuita [J]. Synth. Commun., 2005, 35: 1915 ~ 1920.

11. Xiang-Shan Wang, Zhao-Sen Zeng, Da-Qing Shi, Xian-Yong Wei uye Zhi-Min Zong Chimiro che 2-amino-3-cyano-4- (4-methylphenyl) -6-methoxyl-1, 4,9,10 -tetrahydrobenzo [f] chromene [J]. J. Chem. Cryst. 2005, 35 (3): 243 ~ 247.

12. Xiang-Shan Wang, Zhao-Sen Zeng, Da-Qing Shi, Xian-Yong Wei, Zhi-Min Zong. The crystal structure and unclassical pyran conformation ya 2-amino-7-methyl-4- (3-nitrophenyl) -5-oxo-4H, 5H-pyran [4,3-b] pyran-3-carbonirrile [J]. J. Chem. Res. (S), 2005, 12: 775 ~ 777.

1 yakarangarira "Zhaosen Zeng Ph.D. chidimbu chehumbowo chemamiriro efundo ne kodzero"

  1. thiet ke catalog hcm

    Great post. Zvinyorwa zvinonyatsoshanda, ndanga ndakatarisa ichi chinyorwa kwenguva yakareba. Ndinokutendai uye nerombo rakanaka, Kutumira, chigadzirwa chemiti yakachengetedzwa.

Leave a Reply

Your kero e haangazozikamwi ichibudiswa.